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gained weight on tirzepatide outperformed semaglutide weight-loss drug results in real world patients, study shows Gained Weight on Tirzepatide After

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Liu P, Wu D, Duan J, Xiao H, Zhou Y, Zhao L, et al

Neuromuscul Disord 31:11131123

Of interest, IGF-IR mRNA is temporally consistent with the IGF-I expression, except from the mural granulose cells, where IGF-IR production is preserved, suggesting a paracrine/endocrine dependence for the IGF-I effects at this level[101]